Vancomycin hydrochloride
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Section 1 - Chemical Product and Company Identification
MSDS Name: Vancomycin hydrochloride
Catalog Numbers: SC-18931
Section 2 - Composition, Information on Ingredients
CAS# 1404-93-9
Chemical Name Vancomycin hydrochloride
Percent 98%
EINECS/ELINCS: Unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38 43
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. May cause sensitization by skin contact.
Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. May be harmful if absorbed through the skin. May cause sensitization by skin contact.
Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation: Causes respiratory tract irritation. May be harmful if inhaled.
Chronic: No information found.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Get medical aid. Wash mouth out with water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Do not let this chemical enter the environment.
Section 7 - Handling and Storage
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Store in a tightly closed container. Store in a dry area. Keep refrigerated. (Store below 4°C/39°F.) Store under nitrogen.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
Physical State: Powder
Color: Off-white
Odor: Odorless
pH: 2.5-4.5 (5% aq.sol.)
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point:: Not available.
Freezing/Melting Point:: Not available.
Autoignition Temperature: Not available
Flash Point: Not available.
Decomposition Temperature:Not available.
Solubility: 50 g/l
Specific Gravity/Density:
Molecular Formula:C66H75Cl2N9O24.HCl
Molecular Weight:: 1485.73
Section 10 - Stability and Reactivity
Chemical Stability: Hygroscopic: absorbs moisture or water from the air.
Conditions to Avoid: Incompatible materials, dust generation, exposure to moist air or water.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: has not been reported.
Section 11 - Toxicological Information
RTECS#: CAS# 1404-93-9: YW4380000
LD50/LC50: RTECS:
CAS# 1404-93-9:Oral, mouse: LD50 = >5 gm/kg;
Oral, rat: LD50 = >10 gm/kg;
Carcinogenicity: Vancomycin hydrochloride, 98% - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
Other Studies: See actual entry in RTECS for complete information. The toxicological properties have not been fully investigated.
Section 12 - Ecological Information
Do not empty into drains.
Section 13 - Disposal Considerations
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - Transport Information
Shipping Name: Not regulated
UN Number: not available
Packing Group: not available
WGK Germany: not available
Section 15 - Regulatory Information
European Labeling in Accordance with EC Directives
Hazard Class: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system and skin.
R 43 May cause sensitization by skin contact.
Safety Phrases:
S 22 Do not breathe dust
S 24/25 Avoid contact with skin and eyes.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection
Canada
CAS#1404-93-9 is not listed on Canada's NDSL List
US Federal
TSCA
CAS#1404-93-9 is not listed on the TSCA Inventory. It is for research and development use only.
Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.
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