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Dehydroepiandrosterone

Material Safety Data Sheet
Dehydroepiandrosterone

Section 1 - Chemical Product and Company Identification
MSDS Name: Dehydroepiandrosterone
Catalog Numbers: 86-36279 

Section 2 - Composition, Information on Ingredients 
CAS#53-43-0
Chemical Name: Dehydroepiandrosterone
Percent  99%
EINECS/ELINCS: 200-175-5
Hazard Symbols: Xi
Risk Phrases: 36/37/38
Identified uses : Laboratory chemicals, Manufacture of substances

Section 3 - Hazards Identification 
EMERGENCY OVERVIEW
Harmful if swallowed. May cause irritation to eyes, respiratory system and skin.

3.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Skin irritation (Category 2), H315
Eye irritation (Category 2), H319
Specific target organ toxicity - single exposure (Category 3), H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Xi   Irritant    R36/37/38
For the full text of the R-phrases mentioned in this Section, see Section 16.
3.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram 
Signal word: Warning
Hazard statement(s)
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Precautionary statement(s)
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Supplemental Hazard Statements: none
Safety data sheet available on request.
2.3 Other hazards - none

Section 4 - First Aid Measures 
4.1 Description of first aid measures
General advice: Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact: Wash off with soap and plenty of water. Consult a physician.
In case of eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed: no data available

Section 5 - Fire Fighting Measures 
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture: Carbon oxides
5.3 Advice for firefighters: Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information: no data available

Section 6 - Accidental Release Measures 
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions: Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections: For disposal see section 13.

Section 7 - Handling and Storage 
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
7.3 Specific end use(s)
A part from the uses mentioned in section 1.2 no other specific uses are stipulated

Section 8 - Exposure Controls, Personal Protection 
8.1 Control parameters: Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.  Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Body Protection
Impervious clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Do not let product enter drains.

Section 9 - Physical and Chemical Properties 
Physical State: Powder
Color: Beige
Odor: Not available
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available
Freezing/Melting Point: 149 - 151 °C - lit.
Autoignition Temperature: Not available
Flash Point: No data available
Decomposition Temperature:Not available.
Specific Gravity/Density: No data available
Molecular Formula: C19H28O2
Molecular Weight: 288.42

Section 10 - Stability and Reactivity 
Chemical Stability: Stable under recommended storage conditions.
Conditions to Avoid: No decomposition if used and stored according to specifications..
Incompatibilities with Other Materials: Strong oxidizing agents
Hazardous Decomposition Products: Other decomposition products - no data available
In the event of fire: see section 5

Section 11 - Toxicological Information 
Acute toxicity: LD50 Oral - rat - > 10.000 mg/kg:  
Carcinogenicity:
No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Other Studies: The toxicological properties have not been fully investigated.
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation.
Additional Information
RTECS: BV8396000
Electrolyte imbalance., To the best of our knowledge, the chemical, physical, and toxicological properties  have not been thoroughly investigated.

Section 12 - Ecological Information 
Additional ecological information:

General notes: no data available

Section 13 - Disposal Considerations
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging: Dispose of as unused product.

Section 14 - Transport Information 
14.1 UN number
ADR/RID:  -                                                   IMDG:  -                                                 IATA:  -
14.2 UN proper shipping name
ADR/RID:  Not dangerous goods
IMDG:  Not dangerous goods
IATA:  Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID:  -                                                   IMDG:  -                                                 IATA:  -
14.4 Packaging group
ADR/RID:  -                                                   IMDG:  -                                                 IATA:  -
14.5 Environmental hazards
ADR/RID: no                                                 IMDG Marine Pollutant: no                     IATA: no
14.6 Special precautions for user
no data available

Section 15 - Regulatory Information
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture: no data available
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out

Section 16 - Additional Information
Full text of H-Statements referred to under sections 2 and 3.
Eye Irrit. Eye irritation
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Skin Irrit. Skin irritation
STOT SE Specific target organ toxicity - single exposure
Full text of R-phrases referred to under sections 2 and 3
Xi Irritant
R36/37/38 Irritating to eyes, respiratory system and skin.