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Cytosine

Material Safety Data Sheet
Cytosine
Section 1 - Chemical Product and Company Identification
MSDS Name: Cytosine
Catalog Numbers: 86-15210

Section 2 - Composition, Information on Ingredients 
CAS#71-30-7
Chemical Name: Cytosine
Percent  99%
EINECS/ELINCS: 200-749-5
Hazard Symbols: Xi
Risk Phrases: 36/37/38

 

Section 3 - Hazards Identification 
3.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Skin irritation (Category 2)
Eye irritation (Category 2)
Specific target organ toxicity - single exposure (Category 3)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Irritating to eyes, respiratory system and skin.

3.2 Label elements
Labelling according Regulation (EC) No 1272/2008 [CLP]
Pictogram    
Signal word Warning
Hazard statement(s)
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Precautionary statement(s)
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove  contact lenses, if present and easy to do. Continue rinsing.
Supplemental Hazard Statements: none

Section 4 - First Aid Measures
4.1 Description of first aid measures
General advice: Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact: Wash off with soap and plenty of water. Consult a physician.
In case of eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
4.3 Indication of any immediate medical attention and special treatment needed: no data available

Section 5 - Fire Fighting Measures 
5.1 Extinguishing media
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture: Carbon oxides, nitrogen oxides (NOx); Carbon oxides, nitrogen oxides (NOx)
5.3 Advice for firefighters: Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information: no data available

Section 6 - Accidental Release Measures 
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure  adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
6.2 Environmental precautions: Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections: For disposal see section 13.

Section 7 - Handling and Storage 
7.1 Precautions for safe handling: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection.
7.2 Conditions for safe storage, including any incompatibilities: Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
7.3 Specific end uses: no data available

Section 8 - Exposure Controls, Personal Protection 
8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and  at the end of workday.
Personal protective equipment
Eye/face protection: Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Body Protection: impervious clothing, The type of protective equipment must be selected according to the  concentration and amount of the dangerous substance at the specific workplace.

Section 9 - Physical and Chemical Properties 
a) Appearance Form: powder                  Colour: white
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing point: Melting point/range: > 300 °C - lit.
f) Initial boiling point and boiling range:no data available
g) Flash point no data available
h) Evaporation rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower flammability or explosive limits: no data available
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density no data available
n) Water solubility no data available
o) Partition coefficient: noctanol/water: no data available
p) Autoignition temperature: no data available
q) Decomposition temperature: no data available
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available

Section 10 - Stability and Reactivity 
Chemical Stability: Not available
Conditions to Avoid: no data available
Incompatibilities with Other Materials: Strong oxidizing agents, Strong acids.
Hazardous Decomposition Products: no data.
Hazardous Polymerization:Has not been reported.

Section 11 - Toxicological Information
Acute toxicity: LD50 Intraperitoneal - rat - > 2.222 mg/kg
Skin corrosion/irritation: no data available
Serious eye damage/eye irritation: no data available
Respiratory or skin sensitization: no data available
Germ cell mutagenicity: no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity: no data available
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation.
Specific target organ toxicity - repeated exposure: no data available
Aspiration hazard: no data available
Potential health effects
Inhalation: May be harmful if inhaled. Causes respiratory tract irritation.
Ingestion: May be harmful if swallowed.
Skin: May be harmful if absorbed through skin. Causes skin irritation.
Eyes: Causes serious eye irritation.
Signs and Symptoms of Exposure: To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Additional Information: RTECS: UW7350150

Section 12 - Ecological Information 
12.1 Toxicity: no data available
12.2 Persistence and degradability: no data available
12.3 Bioaccumulative potential: no data available
12.4 Mobility in soil: no data available
12.5 Results of PBT and vPvB assessment: no data available
12.6 Other adverse effects: no data available

Section 13 - Disposal Considerations 

13.1 Waste treatment methods
Product: Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging: Dispose of as unused product.

Section 14 - Transport Information 
14.1 UN number
ADR/RID:  -                                        IMDG:  -                                                 IATA:  -
14.2 UN proper shipping name
ADR/RID:  Not dangerous goods
IMDG:  Not dangerous goods
IATA:  Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID:  -                                        IMDG:  -                                                  IATA:  -
14.4 Packaging group
ADR/RID:  -                                        IMDG:  -                                                  IATA:  -
14.5 Environmental hazards
ADR/RID: no                                      IMDG Marine pollutant: no                      IATA: no
14.6 Special precautions for user: no data available

Section 15 - Regulatory Information 
EThis safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture: no data available
15.2 Chemical Safety Assessment:no data available.

 Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.